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ICR 12000

The ICR 12000 is designed for ultra-high throughput ion channel screening of compound libraries, incorporating multi-channel sampling and enhanced automation features.

Based upon the versatility, precision, and sensitivity of Aurora Biomed’s atomic absorption spectroscopy (AAS) instruments, the ICR 12000 is suitable for both ligand-gated and voltage-gated ion channels using cell-based flux assays. With the robustness of Aurora Biomed’s ICR technology, the reader offers high sensitivity for both electrogenic and non-electrogenic channels and transporters.

The incredible 60,000 sample per day throughput of the ICR 12000 enables ion channel researchers to access compound QT liability early in the drug discovery process.

Specifications

  • Medium Throughput: Up to 5000 wells/day

  • Single Channel: Measures 1 sample at a time

  • Minimum sample volume: 50 µl

  • Accommodation: 96/384-well microplates

  • Footprint: H.67 cm X W.55 cm X D.37 cm

  • Fuel Source: Acetylene / Compressed Air

  • Options: Plate Stacker / Bar Code Reader

  • Sensitivity: 0.05 ppm detection limit

  • Precision: < 5% CV

Features & Benefits

  • Programmable and automated solution for up to 60,000 wells/day

  • Automatic dilution, calibration and cleaning

  • Integrated plate stacker & bar code reader

  • Sample dilution not required

  • High sensitivity

  • On-line dilution

  • Eliminates quenching effects associated with fluorescence

  • Removes need to work with hazardous radioisotopes

  • Avoids work restrictions posed by Rb’s short half-life

  • Ideal for hERG channel assays

  • Can assess both electrogenic and non-electrogenic transporters

ICR 12000 Enquiry

For more information or to arrange a call from one of the Cea Analytical Team, please complete the contact form below.  If your enquiry is urgent, please call us on 1300 552 725.

ICR 12000 Enquiry

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